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- Joseph Roland D Espiritu.
- Division of Pulmonary, Critical Care, and Sleep Medicine, Saint Louis University School of Medicine, 3635 Vista Avenue at Grand Boulevard, PO Box 15250, Saint Louis, MO 63110-0250, USA. espiritu@slu.edu
- Clin. Geriatr. Med. 2008 Feb 1;24(1):1-14, v.
AbstractNormal aging is accompanied by changes in the sleep quality, quantity, and architecture. Specifically, there appears to be a measurable decrease in the ability of the healthy elderly to initiate and maintain sleep, accompanied by a decrease in the proportion of the deeper, more restorative slow-wave sleep and rapid eye movement sleep. There is epidemiologic evidence that this impaired ability to initiate, maintain, and ultimately achieve good quality, optimal sleep may be a marker of increased mortality and neurocognitive dysfunction. Possible mechanisms related to these age-related changes in sleep include age-related changes in circadian modulation, homeostatic factors, cardiopulmonary function, and endocrine function. This article describes the normal changes in sleep physiology in the elderly.
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