• Louisa S Schilling and John D Markman.
• Department of Neuroscience, University of Toronto, 27 Kings College Circle, Toronto, ON M5S, Canada; Translational Pain Research Program, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Rochester, NY 14642, USA.
• Rheum. Dis. Clin. North Am. 2016 Feb 1; 42 (1): 137-55, ix.

AbstractTargeted interventional delivery of corticosteroids remains a mainstay of treatment for spinal pain syndromes because this approach has a wider therapeutic index than other approaches. The best evidence for analgesic efficacy is in subacute radicular syndromes associated with new-onset or recurrent lumbar radiculitis. Complications often relate to drug delivery technique as much as actions of the steroid itself and require careful consideration and vigilance by the administering physician. Considerable uncertainty persists concerning which patients with chronic pain are most likely to benefit from corticosteroid injections. Matching this treatment option with specific spinal pain syndromes remains a major challenge. Copyright © 2016 Elsevier Inc. All rights reserved.

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