• Med J Armed Forces India · Oct 2012

    Review

    Local anesthetic systemic toxicity (LAST) - Should we not be concerned?

    • Rakhee Goyal and R N Shukla.
    • Classified Specialist (Anaesthesia and Critical Care), Command Hospital (SC), Pune 411040, India.
    • Med J Armed Forces India. 2012 Oct 1;68(4):371-5.

    AbstractLocal anesthetics are one of the most commonly used drugs in the field of medicine. Yet little is known about the systemic toxicity that can occur with their overdose. In the last few years, a lot of research has taken place understanding the etiology of the Local anesthetics systemic toxicity (LAST) and the role of lipid emulsion in treating it. There is a need to increase the awareness about LAST and establish a protocol to treat any serious neuro or cardiotoxicity.

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