• Curr Opin Support Palliat Care · Sep 2015

    Review

    Nonopioid medication for the relief of refractory breathlessness.

    • Sarah Awan and Andrew Wilcock.
    • aDepartment of Palliative Care, Nottingham University Hospitals NHS Trust bDivision of Cancer and Stem cells, School of Medicine, University of Nottingham, Nottingham, United Kingdom.
    • Curr Opin Support Palliat Care. 2015 Sep 1; 9 (3): 227-31.

    Purpose Of ReviewTo provide an overview of recent evidence relating to nonopioid medication for the treatment of refractory breathlessness.Recent FindingsA search of publications since 2013 found systematic reviews on phenothiazines and nebulized medications, together with one study examining the use of benzodiazepines and another nebulized furosemide. However, all provided limited data and concluded that further clinical trials are required.SummaryBased on this review, there is insufficient evidence to support the routine use of nonopioid medication in the treatment of refractory breathlessness.

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