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- Jo C Dumville and Christopher Munson.
- Department ofHealth Sciences,University of York, York,UK.jd34@york.ac.uk.
- Cochrane Db Syst Rev. 2012 Jan 1;12:CD006215.
BackgroundA burn wound is a complex and evolving injury, with both local and systemic consequences. Burn treatments include a variety of dressings, as well as newer strategies, such as negative pressure wound therapy (NPWT), which, by means of a suction force that drains excess fluids from the burn, tries to promote the wound healing process and minimise progression of the burn wound.ObjectivesTo assess the effectiveness of NPWT for people with partial-thickness burns.Search MethodsFor this third update we searched the Cochrane Wounds Group Specialised Register (searched 18 May 2012); The Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2012, Issue 5); Ovid MEDLINE (2010 to May Week 2 2012); Ovid MEDLINE (In-Process & Other Non-Indexed Citations 17 May 2012); Ovid EMBASE (2010 to 2012 Week 19); and EBSCO CINAHL (2010 to 16 May 2012).Selection CriteriaAll randomised controlled trials (RCTs) and controlled clinical trials (CCTs) that evaluated the safety and effectiveness of NPWT for partial-thickness burns.Data Collection And AnalysisTwo review authors used standardised forms, and extracted the data independently. We assessed each trial for risk of bias, and resolved differences by discussion.Main ResultsOne RCT, that was an interim report, satisfied the inclusion criteria. We undertook a narrative synthesis of results, as the absence of data and poor reporting precluded us from carrying out any formal statistical analysis. The trial was at high risk of bias. There was not enough evidence available to permit any conclusions to be drawn regarding the use of NPWT for treatment of partial-thickness burn wounds.
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