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- A L P Albuquerque, L E Nery, D S Villaça, T Y S Machado, C C Oliveira, A T Paes, and J A Neder.
- Pulmonary Function and Clinical Exercise Physiology Unit, Respiratory Division, Dept of Medicine, Federal University of Sao Paulo, Sao Paulo, Brazil.
- Eur. Respir. J. 2006 Nov 1;28(5):939-44.
AbstractThe inspiratory-to-total lung capacity ratio or "inspiratory fraction" (inspiratory capacity(IC)/total lung capacity (TLC)) may be functionally more representative than traditional indices of resting airflow limitation and lung hyperinflation in patients with chronic obstructive pulmonary disease (COPD). In the present retrospective study, a comparison was made of the individual performance of post-bronchodilator IC, IC/TLC and forced expiratory volume in one second (FEV(1)) in predicting a severely reduced peak oxygen uptake (V'(O(2)); <60% predicted) in 44 COPD patients Global Initiative for Chronic Obstructive Lung Disease stages II-III (post-bronchodilator FEV(1) ranging from 31-79% pred). Patients with lower IC/TLC values (
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