• Am. J. Hematol. · May 1991

    Case Reports

    Recombinant human erythropoietin for a Jehovah's Witness with anemia of thermal injury.

    • L K Boshkov, E E Tredget, and A Janowska-Wieczorek.
    • Department of Medicine, University of Alberta Hospital, Edmonton, Canada.
    • Am. J. Hematol. 1991 May 1;37(1):53-4.

    AbstractWe report the use of recombinant human erythropoietin (rh-Ep) as an alternative to transfusion therapy in a burn victim who was a Jehovah's Witness and refused blood transfusion. Despite endogenous elevated erythropoietin levels, the patient was reticulocytopenic and administration of rh-Ep was accompanied by a 10-fold increase in reticulocyte response and a rise in hemoglobin from 7.4 to 10.4 g/dl over a 12-day period. We suggest that the exogenously administered erythropoietin overcame a clinically inadequate endogenous erythropoietin response.

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