• Almudena Moreno Elola-Olaso, Daniel L Davenport, Jonathan C Hundley, Michael F Daily, and Roberto Gedaly.
• Transplantation and Hepatobiliary Center, University of Kentucky College of Medicine, 800 Rose Street, Lexington, KY 40536-0293, USA.
• HPB (Oxford). 2012 Feb 1;14(2):136-41.

Background  Postoperative infections are frequent complications after liver resection and have significant impact on length of stay, morbidity and mortality. Surgical site infection (SSI) is the most common nosocomial infection in surgical patients, accounting for 38% of all such infections.Objectives  This study aimed to identify predictors of SSI and organ space SSI after liver resection.Methods  Data from the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) database for patients who underwent liver resection in 2005, 2006 or 2007 in any of 173 hospitals throughout the USA were analysed. All patients who underwent a segmental resection, left hepatectomy, right hepatectomy or trisectionectomy were included.Results  The ACS-NSQIP database contained 2332 patients who underwent hepatectomy during 2005-2007. Rates of SSI varied significantly across primary procedures, ranging from 9.7% in segmental resection patients to 18.3% in trisectionectomy patients. A preoperative open wound, hypernatraemia, hypoalbuminaemia, elevated serum bilirubin, dialysis and longer operative time were independent predictors for SSI and for organ space SSI.Conclusions  These findings may contribute towards the identification of patients at risk for SSI and the development of strategies to reduce the incidence of SSI and subsequent costs after liver resection.© 2011 International Hepato-Pancreato-Biliary Association.

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