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Regional anesthesia · Sep 1995
Case ReportsEpidural analgesia in a preeclamptic parturient after normalization of a prolonged bleeding time with DDAVP.
- R Y Fragneto and S Datta.
- Department of Anesthesiology, Medical College of Virginia, Richmond 23298-0695, USA.
- Reg Anesth. 1995 Sep 1;20(5):448-51.
Background And ObjectivesDespite several advantages to the use of epidural analgesia for the management of labor pain in preeclamptic parturients, this procedure is withheld from many such patients owing to associated thrombocytopenia and platelet dysfunction.MethodsA preeclamptic parturient with mild thrombocytopenia and platelet dysfunction manifested by a prolonged bleeding time received intravenous DDAVP (0.3 microgram/kg) in an attempt to correct her coagulation abnormality.ResultsThe patient's bleeding time was normalized with DDAVP administration, allowing her to receive epidural analgesia.ConclusionsPreeclampsia-induced platelet dysfunction might be corrected with DDAVP: A controlled study is required before its routine use can be advocated.
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