• Neuroscience letters · Nov 1998

    Prediction of migraine attacks using a slow cortical potential, the contingent negative variation.

    • P Kropp and W D Gerber.
    • Institute of Medical Psychology, Center of Nervous Diseases, Kiel, Germany. kropp@med-psych.uni-kiel.de
    • Neurosci. Lett. 1998 Nov 27;257(2):73-6.

    AbstractAmplitudes of contingent negative variation (CNV) as a slow cortical potential in migraine patients were recorded before and after migraine attacks. The level of CNV amplitudes, especially of the early component, showed a trend in rise of negativity 1 day before the attack, whereas amplitudes were normal for 2-3 days following an attack. In most cases the attack occurred when the CNV amplitude showed maximum negativity. We conclude that migraine-susceptible days are indicated by a high CNV amplitude the day before the attack.

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