• Emerg Med Australas · Aug 2008

    Review

    Review article: hypertonic saline use in the emergency department.

    • Colin J Banks and Jeremy S Furyk.
    • Emergency Department, The Townsville Hospital, Douglas, Queensland, Australia. felix@uni-greifswald.de
    • Emerg Med Australas. 2008 Aug 1;20(4):294-305.

    AbstractHypertonic saline (HS) is being increasingly used for the management of a variety of conditions, most notably raised intracranial pressure. This article reviews the available evidence on HS solutions as they relate to emergency medicine, and develops a set of recommendations for its use. To conclude, HS is recommended as an alternative to mannitol for treating raised intracranial pressure in traumatic brain injury. HS is also recommended for treating severe and symptomatic hyponatremia, and is worth considering for both recalcitrant tricyclic antidepressant toxicity and for cerebral oedema complicating paediatric diabetic ketoacidosis. HS is not recommended for hypovolaemic resuscitation.

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