• Resuscitation · Apr 2016

    Randomized Controlled Trial Multicenter Study Pragmatic Clinical Trial

    Design and implementation of the Resuscitation Outcomes Consortium Pragmatic Airway Resuscitation Trial (PART).

    • Henry E Wang, David K Prince, Shannon W Stephens, Heather Herren, Mohamud Daya, Neal Richmond, Jestin Carlson, Craig Warden, M Riccardo Colella, Ashley Brienza, Tom P Aufderheide, Ahamed H Idris, Robert Schmicker, Susanne May, and Graham Nichol.
    • Department of Emergency Medicine, University of Alabama School of Medicine, Birmingham, AL, United States. Electronic address: hwang@uabmc.edu.
    • Resuscitation. 2016 Apr 1; 101: 576457-64.

    AbstractAirway management is an important component of resuscitation from out-of-hospital cardiac arrest (OHCA). The optimal approach to advanced airway management is unknown. The Pragmatic Airway Resuscitation Trial (PART) will compare the effectiveness of endotracheal intubation (ETI) and Laryngeal Tube (LT) insertion upon 72-h survival in adult OHCA. Encompassing United States Emergency Medical Services agencies affiliated with the Resuscitation Outcomes Consortium (ROC), PART will use a cluster-crossover randomized design. Participating subjects will include adult, non-traumatic OHCA requiring bag-valve-mask ventilation. Trial interventions will include (1) initial airway management with ETI and (2) initial airway management with LT. The primary and secondary trial outcomes are 72-h survival and return of spontaneous circulation. Additional clinical outcomes will include airway management process and adverse events. The trial will enroll a total of 3000 subjects. Results of PART may guide the selection of advanced airway management strategies in OHCA.Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

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