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Case Reports
[Tuberculoma and tuberculous meningeal-radiculitis with paradoxical progression during treatment].
- D Rabar, B Issartel, P Petiot, A Boibieux, C Chidiac, and D Peyramond.
- Service de maladies infectieuses et tropicales, Hôpital de la Croix-Rousse, Lyon.
- Presse Med. 2005 Jan 15;34(1):32-4.
IntroductionNeuromeningeal tuberculosis of deleterious, paradoxical, progression despite appropriate antibiotic therapy is rare.ObservationAn immunocompetent woman exhibited an immediately disseminated form of tuberculosis with progressive neurological involvement associating expanding intracranial tuberculomas and meningeal-radiculitis despite adapted anti-tuberculosis quadritherapy.DiscussionDuring anti-tuberculosis therapy clinical worsening is rare, particularly when 2 different manifestations are associated and the worsening occurs in an immunocompetent patient. This possibility should be systematically evoked in such cases. The explanation of this phenomenon is still unclear.
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