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Randomized Controlled Trial Clinical Trial
A single dose of milrinone facilitates separation from cardiopulmonary bypass in patients with pre-existing left ventricular dysfunction.
- E B Lobato, O Florete, and H L Bingham.
- Department of Anesthesiology, University of Florida College of Medicine, Gainesville, USA.
- Br J Anaesth. 1998 Nov 1;81(5):782-4.
AbstractMilrinone is used during cardiac surgery to facilitate separation from cardiopulmonary bypass (CPB) and/or to treat myocardial dysfunction in the post-bypass period. We have demonstrated, in patients with preoperative depression of systolic function undergoing aorto-coronary artery bypass surgery, sustained improvement in cardiac function after a single loading dose of milrinone 50 micrograms kg-1, administered at the end of bypass, thus significantly decreasing the need for beta-agonist therapy.
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