• Clin. Infect. Dis. · Aug 2009

    Kinetics of pertussis immune responses to tetanus-diphtheria-acellular pertussis vaccine in health care personnel: implications for outbreak control.

    • Kathryn B Kirkland, Elizabeth A Talbot, Michael D Decker, and Kathryn M Edwards.
    • Department of Medicine, Section of Infectious Disease and International Health, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire 03756, USA. kathy.kirkland@hitchcock.org
    • Clin. Infect. Dis. 2009 Aug 15;49(4):584-7.

    AbstractWe assessed the kinetics of the humoral immune response to pertussis antigens following vaccination of health care personnel with adult tetanus-diphtheria-acellular pertussis vaccine (Tdap). By 2 weeks after vaccination, 88%-94% of subjects demonstrated a booster response. This brisk response of adults to Tdap supports a role for vaccination in pertussis outbreak control.

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