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Anaesth Intensive Care · Feb 2003
Case ReportsAnti-factor Xa monitoring of anticoagulation during cardiopulmonary bypass in a patient with antiphospholipid syndrome.
- M J Lennon, N M Thackray, and N M Gibbs.
- Department of Anaesthesia, Sir Charles Gairdner Hospital, Hospital Avenue, Nedlands, W.A. 6009.
- Anaesth Intensive Care. 2003 Feb 1;31(1):95-8.
AbstractThe activated clotting time (ACT) may be an unreliable monitor of coagulation for patients with the antiphospholipid syndrome. We describe a patient with antiphospholipid syndrome in whom adequate anticoagulation during cardiopulmonary bypass was confirmed by monitoring both the ACT and anti-factor Xa levels. The cardiopulmonary bypass was uneventful, and there were no thrombotic or bleeding complications. The use of anti-factor Xa levels provided confirmation of adequate anticoagulation (and reversal of anticoagulation) that was not possible using the ACT alone.
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