• Sarah Valeska Pattberg, Dong-In Shin, Stephan Degener, Andreas Boldt, Ingo Stamm, Beatrice Tonnellier, and Marc Horlitz.
• Fakultät für Medizin, Universität Witten/Herdecke, Witten.
• Med Klin. 2008 Jun 15;103(6):441-4.

BackgroundTakotsubo cardiomyopathy is characterized by a transient left ventricular dysfunction. The resulting acute symptoms including electrocardiographic changes and elevated myocardial biomarkers often mimic an acute myocardial infarction. However, obstructive coronary artery disease can be excluded by angiography. There is only little information available in the literature. The precise pathophysiology is still unknown.Case ReportThe case of a 56-year-old woman with typical manifestation of a highly symptomatic Takotsubo cardiomyopathy is described. The diagnosis was suspected by angiographic absence of obstructive coronary disease. During the following days, Takotsubo cardiomyopathy was confirmed by cardio-MRI and echocardiography. The patient was treated with drugs. 12 days after admission, cardiac function was completely restored. The patient was discharged without showing any symptoms.ConclusionAlthough takotsubo cardiomyopathy is rather rare, it should be considered as a relevant differential diagnosis mimicking acute myocardial infarction. Despite a generally good prognosis under conservative treatment, complications are reported in 17.7% of all cases in the literature. Therefore, intensive treatment and monitoring are mandatory.

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