• Giuseppe M Rovera, Robert E Schoen, Beth Goldbach, Douglas Janson, Geoffrey Bond, Jorge Rakela, Toby O Graham, Stephen O'Keefe, and Kareem Abu-Elmagd.
• Thomas E. Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213-2582, USA.
• Jpen Parenter Enter. 2003 Jul 1;27(4):252-9.

ObjectiveThe objective of this study was to describe the dynamics of nutrition management of intestinal transplant recipients and allograft functional autonomy.MethodsIntestinal absorptive functions and recipient nutritional status were monitored during the 12-month study period. Absorption was evaluated with D-xylose absorption and fecal fat excretion. Indices for nutrition were body weight, anthropometric measures, and serum albumin.ResultsBefore transplant, all patients were total parenteral nutrition (TPN) dependent and well nourished. By the first postoperative month, all 22 recipients were tolerating enteral feeding. By 3 months, all recipients had begun oral feeding, with 13 off TPN and 7 off enteral feeds. By 6 months, 16 recipients were off TPN, and by the end of the 12th month, 17 (77%) were free of TPN. Although all 22 recipients were completely weaned off TPN during the first posttransplant year, 10 required temporary reinstitution of therapy at different points. Full nutritional autonomy was achieved at 3 months by 3 recipients, at 6 months by 8 recipients, and at 12 months by 12 (55%) recipients.ConclusionsThese results reflect our early experience that led to surgical refinement of the operation and evolution of the recipient postoperative management. Nonetheless, even in this initial cohort, most of the engrafted intestines restored the recipient nutritional autonomy, and all survivors remained well nourished.

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