• Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi · Jun 2012

    [Analysis of effectiveness and incidence of heterotopic ossification after single-level Bryan cervical artificial disc replacement].

    • Wenhua Liu, Bing Zhu, Xiaowei Liu, and Yu Sun.
    • Department of Spinal Surgery, the Affiliated Hospital of Weifang Medical College, Weifang Shandong, 261031, P.R.China. lwhgk@163.com
    • Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2012 Jun 1;26(6):699-702.

    ObjectiveTo evaluate the incidence of heterotopic ossification (HO) after single-level Bryan cervical artificial disc replacement, and to identify the relationship between HO and the effectiveness.MethodsThe clinical data of 48 patients undergoing single-level Bryan cervical artificial disc replacement between October 2005 and October 2007 were reviewed retrospectively. There were 27 males and 21 females with an average age of 40.5 years (range, 33-51 years), including 8 cases of cervical myelopathy, 27 cases of nerve root cervical spondylosis, and 13 cases of mixed cervical spondylosis with an average disease duration of 10.3 months (range, 2-14 months). The involved segments included C3,4 in 3 cases, C4,5 in 6 cases, C5,6 in 30 cases, and C6,7 in 9 cases. The outcomes were evaluated using Visual Analogue Scale (VAS) score, the neck disability index (NDI), and cervical range of motion (ROM). According to patients with or without HO, 48 patients were divided into 2 groups (HO group and no HO group). VAS score, NDI, and cervical ROM were compared between 2 groups at 1, 2, 3, and 4 years after operation.ResultsNo severe complication occurred during and after operation in all patients. Forty-eight patients were followed up 48-72 months (mean, 56.6 months). VAS score and NDI were significantly improved when compared with preoperative values at all time points (P < 0.05); except at 3 days after operation, no significant difference was found in cervical ROM at the other time points when compared with preoperation (P > 0.05). Thirteen patients (27.08%) had HO at 4 years after operation, including 8 cases of grade 1, 3 cases of grade 2, and 2 cases of grade 3. There was no significant difference in VAS score, NDI, and cervical ROM between 2 groups at 1, 2, 3, and 4 years (P > 0.05).ConclusionThe incidence of HO after single-level Bryan cervical artificial disc replacement is relatively high. However, HO has no effect on the cervical ROM and the effectiveness.

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