• Acta Anaesthesiol Scand · May 1991

    Randomized Controlled Trial Comparative Study Clinical Trial

    Tracheal intubation after induction of anaesthesia with thiopentone or propofol without muscle relaxants.

    • J Hovorka, P Honkavaara, and K Korttila.
    • Department of Anaesthesia, Women's Hospital, University of Helsinki, Finland.
    • Acta Anaesthesiol Scand. 1991 May 1;35(4):326-8.

    AbstractThis study was designed to compare the ease of performing laryngoscopy and endotracheal intubation without muscle relaxants after the induction of anaesthesia with either thiopentone or propofol in 106 patients scheduled for elective surgery. Thiopentone (5 mg/kg) or propofol (2.5 mg/kg), supplemented with lidocaine (1.5 mg/kg) and alfentanil (30 micrograms/kg), were used in random order for the induction of anaesthesia. Jaw tone, visualisation of the larynx, position of vocal cords, ease of intubation and tolerance of the tracheal tube were assessed. The jaw was relaxed and the vocal cords were immobile/open in most patients in both groups. Visualisation of the larynx was good in 60 and 46% and intubation was easy in 48 and 22% of the patients given thiopentone and propofol, respectively (P less than 0.05 between groups for intubation). After induction of anaesthesia with thiopentone or propofol, endotracheal intubation is not recommended without the use of muscle relaxants.

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