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Neurol. Med. Chir. (Tokyo) · Mar 2007
Case ReportsSuccessful use of prolonged mild hypothermia in a patient with severe head injury and diffuse brain swelling. Case report.
- Mamoru Murakami, Tetsuya Tsukahara, Hiroyasu Ishikura, Taketo Hatano, Takuya Nakakuki, Eiji Ogino, and Takako Aoyama.
- Department of Neurosurgery, National Hospital Organization Kyoto Medical Center, Kyoto, Japan. mmurakam@tokyo-med.ac.jp
- Neurol. Med. Chir. (Tokyo). 2007 Mar 1;47(3):116-20.
AbstractA 19-year-old female was admitted to our hospital after severe head injury in a traffic accident. On admission, she had no spontaneous respiration, but did have heart beat with a blood pressure of 100/60 mmHg. Neurological examination demonstrated that the Glasgow Coma Scale score was 3 and her pupils were fixed and dilated. Computed tomography (CT) showed diffuse brain swelling with disappearance of the perimesencephalic cistern. Chest CT showed bilateral lung contusions. Mild hypothermia with a target temperature of 33 degrees C was immediately induced, and was continued for 28 days to control the persistent increase in intracranial pressure (ICP). Subsequently, she recovered, and 20 months after admission, could speak and walk with slight hemiparesis on the left. Prolonged mild hypothermia may be effective to control persistent increase in ICP due to diffuse brain swelling.
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