• Circ Cardiovasc Interv · Oct 2008

    Multicenter Study

    Implementation of guidelines for the treatment of acute ST-elevation myocardial infarction: the Cologne Infarction Model Registry.

    • Markus Flesch, Jens Hagemeister, Hans-Joerg Berger, Annett Schiefer, Sylke Schynkowski, Martin Klein, Sassan Sahebdjami, Stephan vom Dahl, Wolfgang Fehske, Rudolf Mies, Michael von Eiff, Holger Pfaff, Peter Frommolt, and Hans-Wilhelm Hoepp.
    • Klinik III für Innere Medizin, Universitaet zu Koeln, Kerpener Strasse 62, 50937 Cologne, Germany. markus.flesch@uni-koeln.de
    • Circ Cardiovasc Interv. 2008 Oct 1;1(2):95-102.

    BackgroundThe aim of the Köln (Cologne) Infarction Model is to examine the feasibility of obligatory treatment of ST-segment-elevation myocardial infarction (STEMI) by first-line percutaneous coronary intervention.Methods And ResultsThe study was performed in Cologne with >1 million citizens, 5 coronary intervention centers, and 11 primary care hospitals. Twelve-lead ECG was available for all emergency medical service (EMS) teams. Partners guaranteed direct transfer of STEMI patients to a catheterization laboratory. A total of 519 patients treated within KIM in 2006 were included in the study. Of these, 24% presented at a primary care hospital, 11% presented directly at a coronary intervention center, 5% were transferred by EMS to primary care hospitals, and 60% were directly transferred by EMS to a catheterization laboratory. In 91% of cases, the catheterization laboratory was notified of the patient's arrival in advance. False-positive ECG diagnosis of STEMI by EMS accounted for 6%. Median treatment times were as follows: from the start of symptoms to first medical contact, 120 minutes; phone to balloon, 70 minutes; and door to balloon, 49 minutes. Of all patients, 93% underwent angiography; 409 patients were treated by coronary intervention, and 24 underwent emergency coronary artery bypass graft. Thrombolysis in Myocardial Infarction grade 3 flow was obtained in 89%. In the hospitals, deaths and new myocardial infarctions were observed in 12.1% and in 1.9% of all patients, respectively.ConclusionsThe Cologne Infarction Model provides evidence for the feasibility of obligatory treatment of STEMI by primary coronary intervention in a metropolitan setting. Acceptance of treatment pathways allowed nearly all STEMI patients to undergo coronary angiography. ECG competence of EMS was excellent. Treatment times were within postulated limits. Results, including mortality, were within a high quality range.

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