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Clinical rheumatology · Oct 2009
Case ReportsSyndrome of periodic fever, aphthous stomatitis, pharyngitis, and adenitis (PFAPA) in siblings.
- Patricia M Valenzuela, Daniela Majerson, Jose L Tapia, and Eduardo Talesnik.
- Department of Pediatrics, Pontificia Universidad Católica de Chile, Lira 85, 5th floor, Santiago, Chile. pvalenzu@med.puc.cl
- Clin. Rheumatol. 2009 Oct 1;28(10):1235-7.
AbstractPFAPA syndrome is characterized by episodes of periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis. PFAPA syndrome usually begins in children under 5 years old and normally has self-resolution. The etiology of PFAPA syndrome remains unknown. In this paper, we report the cases of two different families with siblings with PFAPA syndrome: two sisters and two brothers. To our knowledge, this is the first report of siblings with PFAPA syndrome.
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