• Hélène Raoult, François Eugène, Jean-Christophe Ferré, Jean-Christophe Gentric, Thomas Ronzière, Aymeric Stamm, and Jean-Yves Gauvrit.
• CHU Rennes, Department of Neuroradiology, 2, rue Henri-Le-Guilloux, 35000 Rennes, France. Electronic address: helene.raoult@chu-rennes.fr.
• J Neuroradiology. 2013 Oct 1;40(4):252-9.

Background And PurposeEndovascular mechanical thrombectomy is emerging as a promising therapeutic approach for acute ischemic stroke. This study was aimed at identifying factors influencing outcomes after thrombectomy with a Solitaire stent device.Materials And MethodsForty-five consecutive patients treated with thrombectomy using Solitaire FR were retrospectively included. Clinical, imaging and logistic variables were analyzed. A multivariate logistic regression analysis was used to identify variables influencing clinical outcome, based on discharge NIHSS score change and mRS at 3 months.ResultsPatient mean age and initial NIHSS score was 58 years (range 24-88) and 17 (range 6-32), respectively. An MRI was performed for 80% of patients, showing severe DWI lesion for 28% of patients and associated FLAIR hyperintensity for 58% of patients. Mean time from symptom onset to recanalization was 299min for the 32 ACO and 473min for the 13 PCO. Angiographic efficacy (TICI 2b-3) was achieved for 93% of patients and good clinical outcomes at discharge and at 3 months (mRS≤2) were achieved for 49% and 58% of patients, respectively. Independent prognostic factors for predicting good clinical outcomes at discharge were a short time to recanalization and FLAIR negativity. At 3 months, they were a short time to recanalization and patient age. DWI lesion severity was an associated prognostic factor.ConclusionTwo main prognostic factors for predicting a good clinical outcome after thrombectomy at 3 months were short time from symptom onset to recanalization and patient age.Copyright © 2013 Elsevier Masson SAS. All rights reserved.

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