• P Komericki, R H Grims, W Aberer, and B Kränke.
• Department of Environmental Dermatology and Venereology, Medical University of Graz, Graz, Austria.
• Anaesthesia. 2014 Feb 1;69(2):176-8.

AbstractA 40-year-old man developed anaphylactic shock during surgical replacement of a prolapsed mitral valve during general anaesthesia and an attenuated reaction (Grade 2), three days later during a blood transfusion. Human serum albumin, a component of the fibrinogen concentrate used postoperatively with the erythrocyte concentrate, was identified as the trigger, confirmed by positive skin prick and intradermal tests. Any anaphylaxis during the peri-operative period should cause the clinician to perform allergy tests for identification of the culprit drug and, sometimes, culprit additive. Testing of human serum albumin, acting as hidden allergen, should be included, especially where there has been a blood transfusion.© 2013 The Association of Anaesthetists of Great Britain and Ireland.

31 keywords...

hide…