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J. Clin. Microbiol. · Jun 2005
Case ReportsInability to make a premortem diagnosis of Acanthamoeba species infection in a patient with fatal granulomatous amebic encephalitis.
- Karen C Bloch and Frederick L Schuster.
- Department of Medicine, Division of Infectious Diseases, A-2200 MCN, Vanderbilt University, Nashville, TN 37232-2605, USA. Karen.bloch@vanderbilt.edu
- J. Clin. Microbiol. 2005 Jun 1;43(6):3003-6.
AbstractGranulomatous amebic encephalitis (GAE), an infection of immunocompromised hosts, is almost uniformly fatal. A case of GAE in a patient who failed to mount a serologic response to Acanthamoeba polyphaga is presented. Although Acanthamoeba polyphaga that is sensitive to multiple antimicrobials grew from brain tissue, an inability to make a premortem diagnosis precluded therapy.
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