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- T Russell, S Riazi, N Kraeva, A C Steel, and L A Hawryluck.
- Anaesthesia Department, Sir Charles Gairdner Hospital, Perth, Western Australia. twainrussell@gmail.com
- Anaesthesia. 2012 Sep 1;67(9):1021-4.
AbstractWe present the case of a 20-year-old woman who developed rhabdomyolysis, disseminated intravascular coagulopathy and multi-organ failure induced by ecstasy. Following initial improvement, she developed delayed rhabdomyolysis then haloperidol-induced neuroleptic malignant syndrome, which was treated with a total of 50 mg.kg(-1) dantrolene. Subsequent genetic testing revealed a novel potentially pathogenic variant in the ryanodine receptor type 1 gene. However, caffeine-halothane contracture testing of the patient's mother who carried the same gene variant was negative for malignant hyperthermia.Anaesthesia © 2012 The Association of Anaesthetists of Great Britain and Ireland.
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