• Hautarzt · Mar 2012

    Case Reports

    [Maculo-papular exanthem with acute renal failure. Drug-induced hypersensitivity syndrome].

    • P A Müller, K Amann, E-B Bröcker, and A Trautmann.
    • Klinik und Poliklinik für Dermatologie, Venerologie und Allergologie, Universitätsklinikum Würzburg, Josef-Schneider-Str. 2, 97080, Würzburg, Deutschland. Tuezolto@hotmail.com
    • Hautarzt. 2012 Mar 1;63(3):223-5.

    AbstractAcute renal failure caused by interstitial nephritis as part of a drug hypersensitivity syndrome constitutes a rare, but potentially life-threatening adverse drug reaction. We describe a patient with a mild maculo-papular rash accompanied by eosinophilia after prolonged treatment with meropenem, vancomycin, and moxifloxacin. Subsequently, a rapidly progressing renal failure developed which dominated the clinical picture. Upon cessation of all suspected drugs and therapy with high-dose steroids for 6 weeks, the renal function slowly returned to normal.

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