• J Intensive Care Med · May 2003

    Review Case Reports

    Intraoperative administration of nitric oxide.

    • Cassie C Dietrich and Joseph D Tobias.
    • Department of Child Health, The University of Missouri, Columbia 65212, USA.
    • J Intensive Care Med. 2003 May 1;18(3):146-9.

    AbstractDespite its therapeutic efficacy in various clinical scenarios in the intensive care unit setting, there are limited reports regarding the intraoperative applications of nitric oxide (NO). The authors present 2 pediatric patients to whom inhaled NO was administered intraoperatively. In one patient, NO was used to treat hypoxemia that developed after the institution of one-lung ventilation during thoracoscopic resection of a bronchiectatic section of lung. In the second patient, NO was used to alleviate pulmonary hypertension and cardiovascular dysfunction with pulmonary artery cross-clamping for placement of a modified Blalock-Taussig shunt. The potential intraoperative applications and techniques for the intraoperative delivery of NO are presented.

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