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Intensive care medicine · Sep 2000
Early signs of critical illness polyneuropathy in ICU patients with systemic inflammatory response syndrome or sepsis.
- A Tennilä, T Salmi, V Pettilä, R O Roine, T Varpula, and O Takkunen.
- Department of Anaesthesia and Intensive Care, Helsinki University Hospital, Finland. arto.tennila@pel.hel.fi
- Intensive Care Med. 2000 Sep 1;26(9):1360-3.
ObjectiveTo evaluate with electromyography the incidence and the time of appearance of neuromuscular abnormality in patients with systemic inflammatory response syndrome (SIRS) and/or sepsis.DesignFollow-up study.SettingIntensive care unit of Helsinki University Hospital, Finland.PatientsNine mechanically ventilated patients with SIRS and/or sepsis.InterventionsElectromyography and conduction velocity measurements on the 2nd-5th day after admission to the intensive care unit.Measurements And ResultsIn all nine patients electromyography revealed signs of neuromuscular abnormality. The means of compound muscle action potential amplitudes of the median and ulnar nerves were decreased. Fibrillation was observed in four patients out of nine.ConclusionBecause neuromuscular abnormalities seem to develop earlier than previously reported, electroneuromyography should be used more frequently as a diagnostic test.
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