• Anesthesia and analgesia · Oct 2003

    Early identification of bacteria leading to central venous catheter contamination.

    • Christian Jeske, Claus Raedler, Achim von Goedecke, Andreas Mayr, Guido Hinterberger, Ch Aspoeck, Cornelia Lass-Floerl, and Arnulf Benzer.
    • Department of Anaesthesia, University Hospital Innsbruck, Austria.
    • Anesth. Analg. 2003 Oct 1;97(4):940-3, table of contents.

    UnlabelledCatheter-related bloodstream infections (CRBSI) are a common problem in patients after central venous catheterization. Using DNA analysis we compared bacteria found on the tip of central venous catheters removed because of clinical signs of CRBSI with bacteria found on needle, dilator, and guidewire used for insertion of these catheters. In five of seven central venous catheters removed because of clinical signs of CRBSI, bacteria on the catheter tip were genetically identical to bacteria found on the insertion device, proving that catheter contamination in these cases was caused by contacting bacteria during the initial puncture. These findings may be important for antibiotic prophylaxis or therapy in patients at risk for CRBSI.ImplicationsIn five of seven central venous catheters removed because of clinical signs of catheter-related blood infections, DNA analysis showed bacteria found on the catheter tip to be identical with bacteria found on the puncture kits used for insertion of these catheters.

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