• Yoshinori Nishiyama.
• Department of Anesthesia, Ehime Rosai Hospital, Niihama 792-8550.
• Masui. 2013 Jul 1;62(7):841-5.

BackgroundThe effects of the addition of remifentanil or nitrous oxide (N2O) on hemodynamics and bispectral index score (BIS) during surgery were exam-ined.MethodsTwenty-four patients for total hysterectomy were allocated into three groups; 1) 8 patients who received neither remifentanil nor N2O (C group), 2) 8 patients who received remifentanil 0.085 microg kg-1 . min-1 (R group) and 3) 8 patients who received 66% of N2O (G group). They were anesthetized with sevoflurane/epidural anesthesia. Mean arterial pressure (MAP), heart rate (HR) and BIS were recorded 3 times (5 minutes after the skin incision, at the moment of uterine extraction and during retroperitoneal closure).ResultsNo significant differences were found in MAP and HR between the C and G group throughout the study, while MAP during retroperitoneal closure and HR at any time points in the R groups were lower than those in the C group. Although BIS in the G group was always lower than that in the C group, no significant differences were found in BIS between the C and R group throughout the study.ConclusionsThe effects of remifentanil on hemodynamics and bispectral index score in patients during surgery under sevoflurane/epidural anesthesia were completely different from those of N2O.

29 keywords...

hide…