• Arthur Halley Barbosa do Vale, Rogério Luiz da Rocha Videira, David Souza Gomez, Maria José Carvalho Carmona, Sara Yume Tsuchie, Cláudia Flório, Matheus Fachini Vane, and Irimar de Paula Posso.
• Disciplina de Anestesiologia, Faculdade de Medicina, Universidade de São Paulo, Instituto Central do HCFMUSP, São Paulo, SP, Brasil. Electronic address: arthurhalley@gmail.com.
• Rev Bras Anestesiol. 2016 Jan 1;66(1):7-11.

Background And ObjectivesThermal injuries and injured areas management are important causes of pain in burned patients, requiring that these patients are constantly undergoing general anesthesia for dressing change. Nitrous oxide (N2O) has analgesic and sedative properties; it is easy to use and widely available. Thus, the aim of this study was to evaluate the analgesic effect of N2O combined with fentanyl in burned patients during dressing change.MethodAfter approval by the institutional Ethics Committee, 15 adult burned patients requiring daily dressing change were evaluated. Patient analgesia was controlled with fentanyl 0.0005% administered by intravenous pump infusion on-demand. Randomly, in one of the days a mixture of 65% N2O in oxygen (O2) was associated via mask, with a flow of 10 L/min (N2O group) and on the other day only O2 under the same flow (control group).ResultsNo significant pain reduction was seen in N2O group compared to control group. VAS score before dressing change was 4.07 and 3.4, respectively, in N2O and control groups. Regarding pain at the end of the dressing, patients in N2O group reported pain severity of 2.8; while the control group reported 2.87. There was no significant difference in fentanyl consumption in both groups.ConclusionsThe association of N2O was not effective in reducing opioid consumption during dressing changes.Copyright © 2014 Sociedade Brasileira de Anestesiologia. Publicado por Elsevier Editora Ltda. All rights reserved.

5 keywords...

hide…