• M C Miranda, J López-Herce, M C Martínez, and A Carrillo.
• Servicio de Cuidados Intensivos Pediátricos, Hospital General Universitario Gregorio Marañón, Universidad Complutense de Madrid, España.
• An Pediatr (Barc). 2012 Jan 1;76(1):16-22.

ObjectivesThe aim of this study is to analyse the relationships and the association between PaO(2)/FiO(2) and SatO(2)/FiO(2with) the duration of admission in Paediatric Intensive Care Units (PICU) and mortality, and to study the relationships between both ratios.Material And MethodsA retrospective study was conducted on PICU patients in whom a gas analysis was performed in the first twenty-four hours of admission. Demographic, clinical and ventilation variables were collected, and the relationship between PaO(2)/FiO(2) and SatO(2)/FiO(2) with days of admission and mortality was determined. Finally, the best cut-off points of SatO(2)/FiO(2) were determined for PaO(2)/FiO(2) values greater and less than 200.ResultsOf 512 patients admitted during one year, a gas analysis was performed on 358, 65% of those in arterial blood. The median duration of hospitalization was two days and there were 11 patient deaths. There was a low negative correlation between the values of PaO(2)/FiO(2) and SatO(2/)FiO(2) on admission to PICU and with duration of admission, and an inverse association with mortality (P<.01). This association was stronger for the PaO(2)/FiO(2) ratio in patients with heart disease, those undergoing invasive mechanical ventilation, and for arterial blood samples. PaO(2)/FiO(2) and SatO(2)/FiO(2) ratios were significantly correlated with each other. A cut-off of 200 for SatO(2)/FiO(2) had a sensitivity of 97.5% for classifying patients with PaO(2)/FiO(2) values lower or higher than 200.ConclusionsPaO(2)/FiO(2) and SatO(2)/FiO(2) index are markers of severity in critically ill patients. In patients who do not have an arterial line, SatO(2)/FiO(2) index can be used for assessment of oxygenation as an indicator of severity in children in critical condition.Copyright © 2011 Asociación Española de Pediatría. Published by Elsevier Espana. All rights reserved.

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