• Trends Cogn. Sci. (Regul. Ed.) · Feb 2015

    Review

    Anesthesia and neuroimaging: investigating the neural correlates of unconsciousness.

    • Alex A MacDonald, Lorina Naci, Penny A MacDonald, and Adrian M Owen.
    • Undergraduate Medical Program, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
    • Trends Cogn. Sci. (Regul. Ed.). 2015 Feb 1;19(2):100-7.

    AbstractIn the past 15 years, rapid technological development in the field of neuroimaging has led to a resurgence of interest in the study of consciousness. However, the neural bases of consciousness and the boundaries of unconscious processing remain poorly understood. Anesthesia combined with functional neuroimaging presents a unique approach for studying neural responses as a function of consciousness. In this review we summarize findings from functional neuroimaging studies that have used anesthetic drugs to study cognition at different levels of conscious awareness. We relate the results to those of psychophysical studies of cognition and explore their potential usefulness in interpreting clinical findings from studies of non-responsive patients.Copyright © 2014 Elsevier Ltd. All rights reserved.

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