• World J Surg Oncol · Jan 2006

    Mesenteric gastrointestinal stromal tumour presenting as intracranial space occupying lesion.

    • Tarun Puri, Gowthaman Gunabushanam, Monica Malik, Shikha Goyal, Anup K Das, Pramod K Julka, and Goura K Rath.
    • Department of Radiotherapy and Oncology, All India Institute of Medical Sciences, New Delhi, India. tarunpuri90@hotmail.com
    • World J Surg Oncol. 2006 Jan 1;4:78.

    BackgroundGastrointestinal stromal tumours (GIST) usually present with non-specific gastrointestinal symptoms such as abdominal mass, pain, anorexia and bowel obstruction.MethodsWe report a case of a 42 year old male who presented with a solitary intracranial space occupying lesion which was established as a metastasis from a mesenteric tumour.ResultsThe patient was initially treated as a metastatic sarcoma, but a lack of response to chemotherapy prompted testing for CD117 which returned positive. A diagnosis of mesenteric GIST presenting as solitary brain metastasis was made, and the patient was treated with imatinib.ConclusionWe recommend that all sarcomas with either an intraabdominal or unknown origin be routinely tested for CD117 to rule out GIST.

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