• The Laryngoscope · Feb 2002

    Clinical Trial

    Use of AlloDerm for coverage of radial forearm free flap donor site.

    • Uttam K Sinha, Charles Shih, Kristi Chang, and Dale H Rice.
    • Department of Otolaryngology, Head and Neck Surgery, University of Southern California School of Medicine, Los Angeles, California 90033, USA. Sinha@hsc.usc.edu
    • Laryngoscope. 2002 Feb 1;112(2):230-4.

    ObjectivesTo evaluate and discuss the role of acellular human dermal matrix (AlloDerm, LifeCell Corp., Branchburg, NJ) graft for coverage of radial forearm free flap donor site.Study DesignProspective, nonrandomized study.MethodsFifty-two consecutive patients underwent harvest of 52 radial forearm fasciocutaneous free flaps. All 52 donor sites were covered by AlloDerm graft. Split-thickness skin graft was not used to reinforce the acellular dermal graft in the series. Clinical phases of healing, duration of healing, and donor site complications were studied.ResultsNo donor site complications except seroma formation in five patients was noted. This was treated by conservative measures. Full range of hand motion was allowed in 3 days. Complete healing occurred within 8 to 12 weeks. Scar contracture after complete healing was minimum in all patients. Range of motion of the hand and fingers during flexion, extension, supination, and pronation was identical on the operated and nonoperated sides.ConclusionAlloDerm graft is a viable alternative to split-thickness skin graft for coverage of the radial forearm free flap donor site.

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