• Neuroscience letters · Jun 1984

    Comparative Study

    Phasic paradoxical sleep precipitates focal motor and limbic seizures.

    • C Cepeda, M T Pacheco, M L Cruz, X Almanza, and M Velasco.
    • Neurosci. Lett. 1984 Jun 15;47(2):179-84.

    AbstractThe facilitatory or inhibitory effect of paradoxical sleep (PxS) was investigated in two models of focal epilepsy: focal motor seizures induced by alumina cream in the frontal cortex and limbic seizures produced by intra-amygdaloid kainic acid microinjections in cats. We found that phasic episodes of PxS could trigger both types of seizures. Interictal spikes were generally blocked during PxS. We conclude that PxS exerts facilitatory or inhibitory effects depending on the particular event under analysis and the degree of epileptogenicity. The capacity of phasic PxS to precipitate focal ictal discharges may depend on ponto-limbic excitatory influences.

      Pubmed     Full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…