• Maíra da Silva Caracas, Sumatra P Jales, Levi H Jales Neto, Joice Carla da Silva Castro, Liliana Mitie Suganuma, Guilherme Henrique Hencklain Fonseca, Sandra Fatima Menosi Gualandro, and José Tadeu Tesseroli de Siqueira.
• Orofacial Pain Team, Dentistry Division, Hospital das Clinicas, Medical School, University of São Paulo, São Paulo, Brazil.
• Oral Surg Oral Med Oral Pathol Oral Radiol. 2013 Feb 1;115(2):e31-5.

AbstractWe report a rare case of aseptic arthritis in the temporomandibular joint of a patient with sickle cell anemia. A 22-year-old woman with sickle cell disease, in the 18th week of gestation, was referred by her hematologist to investigate a sudden mouth opening limitation and severe pain on her left cheek. The patient received a standard pain assessment protocol, clinical examination, and complementary exams (complete blood count, hemoglobin electrophoresis, blood solubility test, panoramic radiograph, and magnetic resonance imaging [MRI]). The blood results were consistent with a sickle cell crisis and the MRI showed an inflammatory process around the left temporomandibular joint. Treatment with opioid analgesics and blood transfusion provided good results. Sickle cell anemia is a disease that can cause arthritis of the temporomandibular joint, and although it is rare, clinicians should be attentive to the differential diagnosis in patients with this disease.Copyright © 2013 Elsevier Inc. All rights reserved.

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