• Der Anaesthesist · Feb 2014

    Review

    [Nalbuphine in pediatric anesthesia.]

    • A-M Schultz-Machata, K Becke, and M Weiss.
    • Universitätsklinik für Anästhesie, Allgemeine Intensivmedizin und Schmerztherapie, Klinische Abteilung für allgemeine Anästhesie und Intensivmedizin, Medizinische Universität Wien, 1090, Wien, Österreich, anette-marie.schultz@meduniwien.ac.at.
    • Anaesthesist. 2014 Feb 1;63(2):135-43.

    AbstractEfficient and safe pediatric perioperative pain therapy in the context of a multimodal pain therapy concept requires a slight to moderate opioid analgesic. Nalbuphine is a nearly ideal opioid for this purpose due to its unique pharmacological properties as a μ-receptor antagonist/κ-receptor agonist and a high safety profile. Nalbuphine is used clinically primarily in postoperative pain therapy administered as a bolus, continuous infusion and patient-controlled analgesia. Furthermore, it is administered in different regimens for pediatric diagnostic and interventional sedation.

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