• Int. J. Pediatr. Otorhinolaryngol. · Sep 2009

    Randomized Controlled Trial

    The effects of topical levobupivacaine on morbidity in pediatric tonsillectomy patients.

    • Süleyman Yilmaz, Yavuz Demiraran, Nermin Akkan, Hüseyin Yaman, Abdulkadir Iskender, Ender Güçlü, and Ozcan Oztürk.
    • Duzce University, Duzce Medical Faculty, Department of ENT and Head & Neck Surgery, Duzce, Turkey. dryilmazsuleyman@yahoo.com
    • Int. J. Pediatr. Otorhinolaryngol. 2009 Sep 1;73(9):1208-10.

    ObjectiveTo reduce the post-tonsillectomy morbidity by swab soaked with 5 ml levobupivacaine hydroclorur (25 mg/10 ml).Study DesignA double-blind prospective randomized controlled clinical study.MethodsIn this randomized double-blind study in group I (30 children, mean age 7.5+/-2.6) we tightly packed swab soaked with 5 ml levobupivacaine hydroclorur (25mg/10 ml) and in group II (21 children, mean age 7.9+/-3.7) we used 5 ml saline swabs into each of the two tonsillar fossae after tonsillectomy for 5 min. We used McGrath's face scale to compare the two groups in respect of pain control.ResultsThere was statistically significant pain relieving effect in the levobupivacaine group in the first 24h (p<0.05). But after 24h pain relieving effect of levobupivacaine was not significant (p>0.05). We did not see any serious complications for both groups. Postoperative morbidity mean results (nausea, vomiting, fever, bleeding, halitosis and ear pain) were not statistically different between the two groups (p>0.05).ConclusionTopical levobupivacaine seems to be a safe and easy medication for postoperative pain control in pediatric tonsillectomy patients.

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