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Interact Cardiovasc Thorac Surg · Mar 2010
Comparative Study Clinical TrialFive years follow-up after Y-graft arterial revascularization: on pump versus off pump; prospective clinical trial.
- Ahmed S E Ramadan, Constantin Stefanidis, William N'Gatchou, Bachar El Oumeiri, Jean-Luc Jansens, Jean-Marie De Smet, Martine Antoine, and Didier De Cannière.
- Department of Cardiac Surgery, Erasme Hospital, University of Brussels (ULB), Route de Lennik, Brussels, Belgium. ahmad_sabry_cts@yahoo.com
- Interact Cardiovasc Thorac Surg. 2010 Mar 1;10(3):423-7.
ObjectivesWe report our comparative experience of on-pump and off-pump full arterial coronary artery bypass grafting (CABG) using both internal mammary arteries (IMAs) anastomosed as a Y-graft.MethodsA single-center clinical study was conducted prospectively between January 2003 and May 2008. It compared the short- and mid-term clinical outcomes of on- and off-pump arterial revascularization where the left internal mammary artery (LIMA) was anastomosed to the left anterior descending (LAD) artery while the free right internal mammary artery (RIMA) graft taking off from the LIMA was used to bypass different coronary targets.ResultsOne hundred and ninety-two patients were divided into 77 on-pump and 115 off-pump procedures based on the intention to treat. The mean age in both groups was 60.2+/-11.7 and 68.1+/-10.6 years, respectively (P<0.05). Mean predictive logistic EuroSCORE was 3.5+/-6.7% for the on-pump group and 7.3+/-8.6% for the off-pump group (P<0.0001). Mean number of distal anastomoses were 2.7+/-0.6 (group ON) and 2.5+/-0.6 (group OFF) (P=NS). Postoperative mortality was two patients (2.6%) in the on-pump group and four patients (3.4%) in the off-pump group (P=0.63). No major adverse cardiac event, no stroke and no late death were reported during the follow-up that averaged 36.5+/-18.6 months. Angina recurrence was three patients (2.6%) in off-pump and two patients (3.5%) in on-pump group (P=NS).ConclusionsThe use of a free RIMA as Y-graft from the LIMA performed off pump eradicates aortic manipulations and provides complete revascularization to high-risk patients with mortality similar to the one of a lower risk population operated on pump. The morbidity and cost was lower in the off-pump group. This advocates for the widespread usage of the technique in high-risk patients.
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