• S Berry, G Roblin, A Williams, A Watkins, and H B Whittet.
• Department of Otorhinolaryngology-Head and Neck Surgery, Singleton Hospital, Swansea, UK.
• Laryngoscope. 2005 Mar 1;115(3):538-40.

ObjectiveTo validate the technique of sleep nasendoscopy using target controlled infusion in symptomatic patients and a control group of asymptomatic individuals.DesignProspective cohort study.SettingDepartment of otolaryngology-head and neck surgery and anesthesia in a teaching hospital.ParticipantsTwo groups of patients were compared and matched for their body mass index. The first group consisted of 53 patients with a history suggestive of obstructive sleep apnea. The second group consisted of 54 patients with partner-confirmed history of no snoring. These patients were undergoing anesthesia for other reasons. Both groups of patients were free of associated otorhinolaryngologic symptoms.Main Outcome MeasureAssessment of production of snoring or obstruction in patients with no documented history of snoring when sedation was administered as part of general anesthesia using target controlled infusion with propofol.Results And ConclusionsNone of the patients in the asymptomatic group snored or obstructed at any level of propofol, and this was clearly significant on comparison with the symptomatic group (P < .001). All of the symptomatic patients were induced to become symptomatic (snoring/obstruction).

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