• Med Klin Intensivmed Notfmed · Nov 2015

    Comparative Study

    [Mild therapeutic hypothermia: Improved survival after resuscitation].

    • T Schlögl, J Schwab, M A Weber, B Witzenbichler, and M A Russ.
    • Klinik für Innere Medizin I, Helios-Amperklinikum Dachau, Krankenhausstr. 15, 85221, Dachau, Deutschland.
    • Med Klin Intensivmed Notfmed. 2015 Nov 1; 110 (8): 597-601.

    BackgroundThe favorable effect of mild therapeutic hypothermia (MTH) on neurologic status as well as on overall survival was shown in several trials; however, MTH is not readily implemented in daily routine.ObjectiveWe examined the effect of the implementation of MTH on neurologic outcome and overall survival in an emergency care hospital.Study Design And MethodsThe data of 68 patients between 09/2010 and 11/2011 who received MTH for 24 h at 33 °C after cardiopulmonary resuscitation (CPR) were compared with prospectively collected data from 180 patients before introduction of MTH (2001-2006). Survival and neurological status at discharge were determined using the Glasgow-Pittsburgh Cerebral Performance Categories (CPC).ResultsMTH raised the percentage of patients with a CPC score of 1 or 2 from 70 % to 85 %. Furthermore, survival increased from 47/180 (26 %) between 01/2000 and 01/2006 to 27/68 (40 %) between 09/2010 and 11/2011.DiscussionImplementation of MTH leads to improved neurological status and overall survival after CPR.

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