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- Wen-Ming Luh, S Lalith Talagala, Tie-Qiang Li, and Peter A Bandettini.
- Functional MRI Facility, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA. wmluh@nih.gov
- Magn Reson Med. 2013 Feb 1;69(2):402-10.
AbstractPseudo-continuous arterial spin labeling (ASL) can provide best signal-to-noise ratio efficiency with a sufficiently long tag at high fields such as 7 T, but it is very sensitive to off-resonance fields at the tagging location. Here, a robust Prescan procedure is demonstrated to estimate the pseudo-continuous ASL radiofrequency phase and gradients parameters required to compensate the off-resonance effects at each vessel location. The Prescan is completed in 1-2 min and is based on acquisition of label/control pair-wise ASL data as a function of the radiofrequency phase increment applied to the pseudo-continuous ASL train. It is shown that this approach can be used to acquire high quality whole-brain pseudo-continuous ASL perfusion data of the human brain at 7 T.Copyright © 2012 Wiley Periodicals, Inc.
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