• J Paediatr Child Health · Mar 2012

    Case Reports

    Cardiac cirrhosis and hepatocellular carcinoma in a 13-year-old treated with doxorubicin microbead transarterial chemoembolization.

    • Jeremy Rosenbaum, John Vrazas, Geoffrey K Lane, and Winita Hardikar.
    • Department of Gastroenterology, Royal Children's Hospital, Melbourne, Victoria, Australia. jeremy.rosenbaum@rch.org.au
    • J Paediatr Child Health. 2012 Mar 1;48(3):E140-3.

    AbstractIncreasing numbers of children are surviving into adulthood following surgery to correct or palliate congenital heart disease. This surgery can occasionally result in long-standing elevated right heart pressures and chronic hepatic venous congestion leading to cardiac cirrhosis. We report the first paediatric case of hepatocellular carcinoma in the setting of cardiac cirrhosis. A 13-year-old girl developed inoperable hepatocellular carcinoma and was treated with transarterial embolization with lipiodol and doxorubicin eluting microbeads. Promoting awareness of this association, even in younger patients, will hopefully result in better surveillance and screening of hepatic complications in survivors of complex cardiac surgery.© 2010 The Authors. Journal of Paediatrics and Child Health © 2010 Paediatrics and Child Health Division (Royal Australasian College of Physicians).

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