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- Seetha Shankaran and Abbot R Laptook.
- Wayne State University, Children's Hospital of Michigan, Detroit, MI 48201, USA. sshankar@med.wayne.edu
- Clin Obstet Gynecol. 2007 Sep 1;50(3):624-35.
AbstractThis chapter will report to the frequency of neonatal hypoxic-ischemic encephalopathy. The pathophysiology and the childhood outcome of encephalopathy due to hypoxia-ischemia will be examined. The limitations of current therapy for this condition and new therapies will be evaluated. Hypothermia seems to offer the most promise as a therapy for neuroprotection in hypoxic-ischemic encephalopathy. The evidence-based trials of hypothermia will be reviewed along with recommendations regarding clinical applications for this therapy and need for long-term follow-up of children receiving this therapy.
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