• Psychiatr. Clin. North Am. · Sep 1996

    Review

    Delirium. Advances in diagnosis, pathophysiology, and treatment.

    • P T Trzepacz.
    • Neuropsychiatry Program, University of Pittsburgh School of Medicine, Pennsylvania, USA.
    • Psychiatr. Clin. North Am. 1996 Sep 1;19(3):429-48.

    AbstractThis article discusses research in the areas of morbidity and mortality, epidemiologic risk factors, phenomenology, pathophysiology, and treatment of delirium. Delirium assessment instruments are reviewed. The neuropathophysiologic understanding of delirium is discussed in the context of important CNS neural circuitry. Pharmacologic treatments of delirium in adults and children are outlined, with particular emphasis on intravenous use of butyrophenone neuroleptics.

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