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J. Matern. Fetal. Neonatal. Med. · Jan 2009
Reliability of procalcitonin in neonatology. Experience in 59 preterm newborns.
- Serena Spada, Antonella Cuccu, Michele Mussap, Marcella Testa, Melania Puddu, Cinzia Pisu, Pietrina Burrai, and Vassilios Fanos.
- Neonatal Pathology and Intensive Therapy, University of Cagliari, Italy.
- J. Matern. Fetal. Neonatal. Med. 2009 Jan 1;22 Suppl 3:96-101.
AbstractProcalcitonin (PCT) has been proposed as an interesting marker in the diagnosis, prognosis, and response to treatment of patient with neonatal sepsis. Fifty-nine neonates (34 males and 25 females) with a mean gestational age of approximately 31 weeks and a mean weight of about 1750 g admitted in the Neonatal Intensive Care Unit of Cagliari (Italy) were evaluated in controls and in infected neonates, before and after 48 h of life. From our experience it emerges that PCT is a marker of early and late neonatal sepsis which is reliable in preterm neonates. A cut-off of 0.5 ng/ml starting from the third day of life appears to be capable of ensuring good test sensitivity and specificity.
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