• The Ochsner journal · Jan 2009

    Induced hypothermia as a neuroprotectant in post-cardiac arrest.

    • Mohi E Alkadri and Paul McMullan.
    • Department of Cardiology, Ochsner Clinic Foundation, New Orleans, LA.
    • Ochsner J. 2009 Jan 1;9(4):278-81.

    AbstractSurvivors of out-of-hospital cardiac arrest frequently suffer devastating effects from anoxic brain injury. Therapeutic hypothermia is the first therapy to show benefit in improving survival as well as limiting neurologic injury. We review the data supporting the use of therapeutic hypothermia in this patient population, the pathophysiologic basis of its neuroprotectant effects, the methods of hypothermic induction, and the clinical application.

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